Textbook of Drug Design and Discovery Pdf Building on the success of their previous variants, the Textbook of Drug Design and Discovery, Fifth Edition, has been extensively revised and updated to give a comprehensive source of data on all aspects of drug discovery and design for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The info is presented within an up-to-date inspection form having an inherent and basic focus on the instructional aspects.
Starting with an introduction to drug discovery and design, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug layout. The authors also discuss drug-like qualities and decision making in medicinal chemistry, chemical composition, natural products in drug discovery, and in vivo imaging in drug discovery.
The center six chapters offer an summary of peptide and protein drug layout, prodrugs in drug design and development, and enzyme inhibitors. The writers also undergo receptors (construction, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (construction, function, and drug binding).
The publication finishes with an evaluation of failed diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.